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Atypical Membrane-embedded Phosphatidylinositol 3,4-Bisphosphate (PI(3,4)P(2))-binding Site on p47(phox) Phox Homology (PX) Domain Revealed by NMR
The Phox homology (PX) domain is a functional module that targets membranes through specific interactions with phosphoinositides. The p47(phox) PX domain preferably binds phosphatidylinositol 3,4-bisphosphate (PI(3,4)P(2)) and plays a pivotal role in the assembly of phagocyte NADPH oxidase. We descr...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366843/ https://ncbi.nlm.nih.gov/pubmed/22493288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.332874 |
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