Synthesis of cyclic oligonucleotides by a modified phosphotriester approach.
Evidence will be presented to show that the allyl group is suitable for the protection of a 3'-terminal phosphodiester function. The latter will be demonstrated by the synthesis, via a phosphotriester approach, of two cyclic tetraribonucleotides [r(AAAA) and r(UAMe2UAMe2)], two cyclic hexadeoxyribon...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1988
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| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336652/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3380690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.10.4607 |
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