Synthesis of cyclic oligonucleotides by a modified phosphotriester approach.

Evidence will be presented to show that the allyl group is suitable for the protection of a 3'-terminal phosphodiester function. The latter will be demonstrated by the synthesis, via a phosphotriester approach, of two cyclic tetraribonucleotides [r(AAAA) and r(UAMe2UAMe2)], two cyclic hexadeoxyribon...

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Publié dans:	Nucleic Acids Res
Auteurs principaux:	de Vroom, E, Broxterman, H J, Sliedregt, L A, van der Marel, G A, van Boom, J H
Format:	Artigo
Langue:	Inglês
Publié:	Oxford University Press 1988
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336652/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3380690/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.10.4607
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