Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents

Thrombosis, or blood clot formation, and its sequelae remain a leading cause of morbidity and mortality, and recurrent thrombosis is common despite current optimal therapy. Protein disulfide isomerase (PDI) is an oxidoreductase that has recently been shown to participate in thrombus formation. While...

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Detalhes bibliográficos
Main Authors: Jasuja, Reema, Passam, Freda H., Kennedy, Daniel R., Kim, Sarah H., van Hessem, Lotte, Lin, Lin, Bowley, Sheryl R., Joshi, Sucharit S., Dilks, James R., Furie, Bruce, Furie, Barbara C., Flaumenhaft, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366406/
https://ncbi.nlm.nih.gov/pubmed/22565308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61228
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