Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents

Thrombosis, or blood clot formation, and its sequelae remain a leading cause of morbidity and mortality, and recurrent thrombosis is common despite current optimal therapy. Protein disulfide isomerase (PDI) is an oxidoreductase that has recently been shown to participate in thrombus formation. While...

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Autori principali: Jasuja, Reema, Passam, Freda H., Kennedy, Daniel R., Kim, Sarah H., van Hessem, Lotte, Lin, Lin, Bowley, Sheryl R., Joshi, Sucharit S., Dilks, James R., Furie, Bruce, Furie, Barbara C., Flaumenhaft, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366406/
https://ncbi.nlm.nih.gov/pubmed/22565308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI61228
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