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Photochemical Generation and Reactivity of the Major Hydroxyl Radical Adduct of Thymidine

[Image: see text] 5,6-Dihydro-5-hydroxythymidin-6-yl radical (1), the major reactive intermediate resulting from hydroxyl radical addition to C5 of the pyrimidine is produced via 350 nm photolysis of a 2,5-dimethylphenylsulfide precursor (2). Competition between O(2) and thiol for 1 suggests that th...

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Bibliografische gegevens
Hoofdauteurs: Maria N., Joanna, Pedro, San, Greenberg, Marc M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366351/
https://ncbi.nlm.nih.gov/pubmed/22616940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301109z
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