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Identification of non-specific hybridization using an empirical equation fitted to non-equilibrium dissociation curves
Non-equilibrium dissociation curves (NEDCs) have the potential to identify non-specific hybridizations on high throughput, diagnostic microarrays. We report a simple method for identification of non-specific signals by using a new parameter that does not rely on comparison of perfect match and misma...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366151/ https://ncbi.nlm.nih.gov/pubmed/22537822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mimet.2012.04.003 |
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