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Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicity
Although oligomeric β-amyloid (Aβ) has been suggested to have an important role in Alzheimer disease (AD), the mechanism(s) of how Aβ induces neuronal cell death has not been fully identified. The balance of pro- and anti-apoptotic Bcl-2 family proteins (e.g., Bcl-2 and Bcl-w versus Bad, Bim and Bax...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3366077/ https://ncbi.nlm.nih.gov/pubmed/22592316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2012.43 |
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