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Pharmacological inhibition of Bax-induced cell death: Bax-inhibiting peptides and small compounds inhibiting Bax

Bax is an essential mediator of mitochondria-dependent programed cell death. Bax belongs to the Bcl-2 family of proteins and its activities are regulated through interaction with other member proteins in the Bcl-2 family. To date, several apoptosis-inducing drugs activating Bax have been developed,...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Jensen, Kelsey, WuWong, David Jasen, Wong, Sean, Matsuyama, Mieko, Matsuyama, Shigemi
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552396/
https://ncbi.nlm.nih.gov/pubmed/30836793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219833624
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