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Bax-induced apoptosis shortens the life span of DNA repair defect Ku70-knockout mice by inducing emphysema
Cells with DNA damage undergo apoptosis or cellular senescence if the damage cannot be repaired. Recent studies highlight that cellular senescence plays a major role in aging. However, age-associated diseases, including emphysema and neurodegenerative disorders, are caused by apoptosis of lung alveo...
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| 發表在: | Exp Biol Med (Maywood) |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
SAGE Publications
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4950276/ https://ncbi.nlm.nih.gov/pubmed/27302174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370216654587 |
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