Soluble Monomeric IgG1 Fc

Antibody fragments are emerging as promising biopharmaceuticals because of their relatively small size and other unique properties. However, compared with full-size antibodies, these antibody fragments lack the ability to bind the neonatal Fc receptor (FcRn) and have reduced half-lives. Fc engineere...

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Bibliografske podrobnosti
Main Authors: Ying, Tianlei, Chen, Weizao, Gong, Rui, Feng, Yang, Dimitrov, Dimiter S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365978/
https://ncbi.nlm.nih.gov/pubmed/22518843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368647
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