Membrane Orientation and Subcellular Localization of Transmembrane Protein 106B (TMEM106B), a Major Risk Factor for Frontotemporal Lobar Degeneration

TMEM106B was identified as a major risk factor in a genome-wide association study for frontotemporal lobar degeneration (FTLD) with TAR DNA-binding protein (TDP)-43 pathology. The most significant association of TMEM106B single nucleotide polymorphisms with risk of FTLD-TDP was observed in patients...

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Main Authors: Lang, Christina M., Fellerer, Katrin, Schwenk, Benjamin M., Kuhn, Peer-Hendrik, Kremmer, Elisabeth, Edbauer, Dieter, Capell, Anja, Haass, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365973/
https://ncbi.nlm.nih.gov/pubmed/22511793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365098
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