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TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

In a genome-wide association study of frontotemporal lobar degeneration with pathological inclusions of TAR DNA-binding protein, significant association was obtained with three single nucleotide polymorphisms at 7p21.3, in a region encompassing the gene TMEM106B. This study also suggested a potentia...

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Bibliografski detalji
Glavni autori: van der Zee, Julie, Van Langenhove, Tim, Kleinberger, Gernot, Sleegers, Kristel, Engelborghs, Sebastiaan, Vandenberghe, Rik, Santens, Patrick, Van den Broeck, Marleen, Joris, Geert, Brys, Jolien, Mattheijssens, Maria, Peeters, Karin, Cras, Patrick, De Deyn, Peter P., Cruts, Marc, Van Broeckhoven, Christine
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044834/
https://ncbi.nlm.nih.gov/pubmed/21354975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awr007
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