Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations

BACKGROUND: The clusterin (CLU) gene has been identified as an important risk locus for Alzheimer’s disease (AD). Although the actual risk–increasing polymorphisms at this locus remain to be identified, we previously observed an increased frequency of rare non-synonymous mutations and small insertio...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Bettens, Karolien, Vermeulen, Steven, Van Cauwenberghe, Caroline, Heeman, Bavo, Asselbergh, Bob, Robberecht, Caroline, Engelborghs, Sebastiaan, Vandenbulcke, Mathieu, Vandenberghe, Rik, De Deyn, Peter Paul, Cruts, Marc, Van Broeckhoven, Christine, Sleegers, Kristel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502563/
https://ncbi.nlm.nih.gov/pubmed/26179372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0024-9
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker