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Reduced secreted clusterin as a mechanism for Alzheimer-associated CLU mutations
BACKGROUND: The clusterin (CLU) gene has been identified as an important risk locus for Alzheimer’s disease (AD). Although the actual risk–increasing polymorphisms at this locus remain to be identified, we previously observed an increased frequency of rare non-synonymous mutations and small insertio...
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| Udgivet i: | Mol Neurodegener |
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| Main Authors: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502563/ https://ncbi.nlm.nih.gov/pubmed/26179372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-015-0024-9 |
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