A role of the frontotemporal lobar degeneration risk factor TMEM106B in myelination

TMEM106B encodes a lysosomal membrane protein and was initially identified as a risk factor for frontotemporal lobar degeneration. Recently, a dominant D252N mutation in TMEM106B was shown to cause hypomyelinating leukodystrophy. However, how TMEM106B regulates myelination is still unclear. Here we...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Brain
Main Authors: Feng, Tuancheng, Sheng, Rory R, Solé-Domènech, Santiago, Ullah, Mohammed, Zhou, Xiaolai, Mendoza, Christina S, Enriquez, Laura Camila Martinez, Katz, Isabel Iscol, Paushter, Daniel H, Sullivan, Peter M, Wu, Xiaochun, Maxfield, Frederick R, Hu, Fenghua
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363491/
https://ncbi.nlm.nih.gov/pubmed/32572497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awaa154
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki