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Novel Role of ADAMTS-5 Protein in Proteoglycan Turnover and Lipoprotein Retention in Atherosclerosis

Atherosclerosis is initiated by the retention of lipoproteins on proteoglycans in the arterial intima. However, the mechanisms leading to proteoglycan accumulation and lipoprotein retention are poorly understood. In this study, we set out to investigate the role of ADAMTS-5 (a disintegrin and metall...

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Detalhes bibliográficos
Main Authors: Didangelos, Athanasios, Mayr, Ursula, Monaco, Claudia, Mayr, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365970/
https://ncbi.nlm.nih.gov/pubmed/22493487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.350785
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