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Role of ADAMTS-5 in Aortic Dilatation and Extracellular Matrix Remodeling

OBJECTIVE—: Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is accompanied by changes in the structure and composition of the aortic ECM (extracellular matrix). The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family of proteases has recently bee...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Fava, Marika, Barallobre-Barreiro, Javier, Mayr, Ursula, Lu, Ruifang, Didangelos, Athanasios, Baig, Ferheen, Lynch, Marc, Catibog, Norman, Joshi, Abhishek, Barwari, Temo, Yin, Xiaoke, Jahangiri, Marjan, Mayr, Manuel
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026471/
https://ncbi.nlm.nih.gov/pubmed/29622560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310562
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