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The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix

In IgA nephropathy (IgAN), IgA immune complexes are deposited in the mesangium and drive inflammation and extracellular matrix (ECM) remodelling. The functional links between IgA deposition, inflammation, and matrix remodelling are not well characterized. We recently performed urine liquid chromatog...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Taylor, Scott, Whitfield, Molly, Barratt, Jonathan, Didangelos, Athanasios
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533710/
https://ncbi.nlm.nih.gov/pubmed/32917786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000448
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