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Essential Role for IKKβ in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells
Plasmacytoid dendritic cells (pDCs) are characterized by their ability to produce high levels of type 1 interferons in response to ligands that activate TLR7 and TLR9, but the signaling pathways required for IFN production are incompletely understood. Here we exploit the human pDC cell line Gen2.2 a...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365954/ https://ncbi.nlm.nih.gov/pubmed/22511786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.345405 |
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