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The wake-promoting effects of hypocretin-1 is attenuated in old rats

Disruption of sleep is a frequent complaint among elderly humans and is also evident in aged laboratory rodents. The neurobiological bases of age-related sleep/wake disruption are unknown. Given the critical role of the hypocretins in sleep/wake regulation, we sought to determine whether the wake-pr...

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Detalhes bibliográficos
Main Authors: Morairty, Stephen R., Wisor, Jonathan, Silveira, Kristy, Sinko, William, Kilduff, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365906/
https://ncbi.nlm.nih.gov/pubmed/19781813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2009.07.017
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