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Trace amine-associated receptor 1 agonism promotes wakefulness without impairment of cognition in Cynomolgus macaques
Trace amine-associated receptor 1 (TAAR1) is a G-protein coupled receptor with affinity for the trace amines. TAAR1 agonists have pro-cognitive, antidepressant-, and antipsychotic-like properties in both rodents and non-human primates (NHPs). TAAR1 agonism also increases wakefulness and suppresses r...
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| Publicat a: | Neuropsychopharmacology |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer International Publishing
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6784974/ https://ncbi.nlm.nih.gov/pubmed/30954024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0386-8 |
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