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Diphenylarsinic Acid Promotes Degradation of Glutaminase C by Mitochondrial Lon Protease
Glutaminase C (GAC), a splicing variant of the kidney-type glutaminase (KGA) gene, is a vital mitochondrial enzyme protein that catalyzes glutamine to glutamate. Earlier studies have shown that GAC proteins in the human hepatocarcinoma cell line, HepG2, were down-regulated by diphenylarsinic acid (D...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365764/ https://ncbi.nlm.nih.gov/pubmed/22493432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362699 |
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