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Diphenylarsinic Acid Promotes Degradation of Glutaminase C by Mitochondrial Lon Protease

Glutaminase C (GAC), a splicing variant of the kidney-type glutaminase (KGA) gene, is a vital mitochondrial enzyme protein that catalyzes glutamine to glutamate. Earlier studies have shown that GAC proteins in the human hepatocarcinoma cell line, HepG2, were down-regulated by diphenylarsinic acid (D...

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Hlavní autoři: Kita, Kayoko, Suzuki, Toshihide, Ochi, Takafumi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365764/
https://ncbi.nlm.nih.gov/pubmed/22493432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362699
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