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Mitochondrial Calpain 10 is Degraded by Lon Protease After Oxidant Injury

Calpain 10 is ubiquitously expressed and is one of four mitochondrial matrix proteases. We determined that over-expression or knock-down of mitochondrial calpain 10 results in cell death, demonstrating that mitochondrial calpain 10 is required for viability. Thus, we studied calpain 10 degradation i...

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Autors principals: Smith, Matthew A., Schnellmann, Rick G.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258974/
https://ncbi.nlm.nih.gov/pubmed/22179018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2011.11.023
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