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Loss of Calpain 10 Causes Mitochondrial Dysfunction during Chronic Hyperglycemia

We showed that renal calpain 10, a mitochondrial and cytosolic Ca(2+)-regulated cysteine protease, is specifically decreased in kidneys of diabetic rats and mice, and is associated with diabetic nephropathy. The goals of this study were to examine renal calpain 10 and mitochondrial dysfunction in st...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smith, Matthew A., Covington, Marisa D., Schnellmann, Rick G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874586/
https://ncbi.nlm.nih.gov/pubmed/22568896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2012.04.020
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