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Damaged Mitochondrial DNA Replication System and the Development of Diabetic Retinopathy
AIM: In the pathogenesis of diabetic retinopathy, retinal mitochondria are damaged, superoxide levels are elevated, and mitochondrial DNA (mtDNA) biogenesis is impaired. mtDNA has a noncoding region, displacement loop (D-loop), which has essential transcription and replication elements, and this reg...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3365359/ https://ncbi.nlm.nih.gov/pubmed/22229649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4333 |
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