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Damaged Mitochondrial DNA Replication System and the Development of Diabetic Retinopathy

AIM: In the pathogenesis of diabetic retinopathy, retinal mitochondria are damaged, superoxide levels are elevated, and mitochondrial DNA (mtDNA) biogenesis is impaired. mtDNA has a noncoding region, displacement loop (D-loop), which has essential transcription and replication elements, and this reg...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tewari, Shikha, Santos, Julia M., Kowluru, Renu A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Mary Ann Liebert, Inc. 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365359/
https://ncbi.nlm.nih.gov/pubmed/22229649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4333
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