High Salt Intake Down-Regulates Colonic Mineralocorticoid Receptors, Epithelial Sodium Channels and 11β-Hydroxysteroid Dehydrogenase Type 2

Besides the kidneys, the gastrointestinal tract is the principal organ responsible for sodium homeostasis. For sodium transport across the cell membranes the epithelial sodium channel (ENaC) is of pivotal relevance. The ENaC is mainly regulated by mineralocorticoid receptor mediated actions. The MR...

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Hlavní autoři: Lienhard, Daniel, Lauterburg, Meret, Escher, Geneviève, Frey, Felix J., Frey, Brigitte M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365073/
https://ncbi.nlm.nih.gov/pubmed/22693583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037898
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