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Epigenetic regulation of 11β-hydroxysteroid dehydrogenase type 2 expression

The enzyme 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) is selectively expressed in aldosterone target tissues, where it confers aldosterone selectivity for the mineralocorticoid receptor by inactivating 11β-hydroxyglucocorticoids. Variable activity of 11βHSD2 is relevant for blood pressure con...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alikhani-Koopaei, Rasoul, Fouladkou, Fatemeh, Frey, Felix J., Frey, Brigitte M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC522246/
https://ncbi.nlm.nih.gov/pubmed/15489962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421647
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