Insulin, CCAAT/Enhancer-Binding Proteins and Lactate Regulate the Human 11β-Hydroxysteroid Dehydrogenase Type 2 Gene Expression in Colon Cancer Cell Lines

11β-Hydroxysteroid dehydrogenases (11beta-HSD) modulate mineralocorticoid receptor transactivation by glucocorticoids and regulate access to the glucocorticoid receptor. The isozyme 11beta-HSD2 is selectively expressed in mineralocorticoid target tissues and its activity is reduced in various diseas...

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Autors principals: Andrieu, Thomas, Fustier, Pierre, Alikhani-Koupaei, Rasoul, Ignatova, Irena D., Guettinger, Andreas, Frey, Felix J., Frey, Brigitte M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136812/
https://ncbi.nlm.nih.gov/pubmed/25133511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105354
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