Optimization of a Novel Peptide Ligand Targeting Human Carbonic Anhydrase IX

BACKGROUND: Carbonic anhydrase IX (CA IX) is a hypoxia-regulated transmembrane protein over-expressed in various types of human cancer. Recently, a new peptide with affinity for human carbonic anhydrase IX (CaIX-P1) was identified using the phage display technology. Aim of the present study is to ch...

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Main Authors: Rana, Shoaib, Nissen, Felix, Marr, Annabell, Markert, Annette, Altmann, Annette, Mier, Walter, Debus, Juergen, Haberkorn, Uwe, Askoxylakis, Vasileios
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365038/
https://ncbi.nlm.nih.gov/pubmed/22693612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038279
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