A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology

Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor hypoxia. Ligands binding this target may be used to visualize hypoxia, tumor manifestation or treat tumors by endoradiotherapy. METHODS: Phage display was performed with a 12...

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Bibliografiske detaljer
Main Authors: Askoxylakis, Vasileios, Garcia-Boy, Regine, Rana, Shoaib, Krämer, Susanne, Hebling, Ulrike, Mier, Walter, Altmann, Annette, Markert, Annette, Debus, Jürgen, Haberkorn, Uwe
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013143/
https://ncbi.nlm.nih.gov/pubmed/21209841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015962
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