A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology

Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor hypoxia. Ligands binding this target may be used to visualize hypoxia, tumor manifestation or treat tumors by endoradiotherapy. METHODS: Phage display was performed with a 12...

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Detalhes bibliográficos
Main Authors: Askoxylakis, Vasileios, Garcia-Boy, Regine, Rana, Shoaib, Krämer, Susanne, Hebling, Ulrike, Mier, Walter, Altmann, Annette, Markert, Annette, Debus, Jürgen, Haberkorn, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013143/
https://ncbi.nlm.nih.gov/pubmed/21209841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015962
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