A New Peptide Ligand for Targeting Human Carbonic Anhydrase IX, Identified through the Phage Display Technology

Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor hypoxia. Ligands binding this target may be used to visualize hypoxia, tumor manifestation or treat tumors by endoradiotherapy. METHODS: Phage display was performed with a 12...

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Main Authors: Askoxylakis, Vasileios, Garcia-Boy, Regine, Rana, Shoaib, Krämer, Susanne, Hebling, Ulrike, Mier, Walter, Altmann, Annette, Markert, Annette, Debus, Jürgen, Haberkorn, Uwe
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013143/
https://ncbi.nlm.nih.gov/pubmed/21209841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015962
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