Challenges in Optimizing a Prostate Carcinoma Binding Peptide, Identified through the Phage Display Technology

The transfer of peptides identified through the phage display technology to clinical applications is difficult. Major drawbacks are the metabolic degradation and label instability. The aim of our work is the optimization of DUP-1, a peptide which was identified by phage display to specifically targe...

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Pubblicato in:Molecules
Autori principali: Askoxylakis, Vasileios, Zitzmann-Kolbe, Sabine, Zoller, Frederic, Altmann, Annette, Markert, Annette, Rana, Shoaib, Marr, Annabell, Mier, Walter, Debus, Jürgen, Haberkorn, Uwe
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259618/
https://ncbi.nlm.nih.gov/pubmed/21321528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16021559
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