Investigation of tumor hypoxia using a two-enzyme system for in vitro generation of oxygen deficiency

BACKGROUND: Oxygen deficiency in tumor tissue is associated with a malign phenotype, characterized by high invasiveness, increased metastatic potential and poor prognosis. Hypoxia chambers are the established standard model for in vitro studies on tumor hypoxia. An enzymatic hypoxia system (GOX/CAT)...

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Main Authors: Askoxylakis, Vasileios, Millonig, Gunda, Wirkner, Ute, Schwager, Christian, Rana, Shoaib, Altmann, Annette, Haberkorn, Uwe, Debus, Jürgen, Mueller, Sebastian, Huber, Peter E
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080288/
https://ncbi.nlm.nih.gov/pubmed/21477371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-6-35
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