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5-Methylcytosine and 5-Hydroxymethylcytosine Spatiotemporal Profiles in the Mouse Zygote

BACKGROUND: In the mouse zygote, DNA methylation patterns are heavily modified, and differ between the maternal and paternal pronucleus. Demethylation of the paternal genome has been described as an active and replication-independent process, although the mechanisms responsible for it remain elusive...

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Bibliografiske detaljer
Main Authors: Salvaing, Juliette, Aguirre-Lavin, Tiphaine, Boulesteix, Claire, Lehmann, Gaëtan, Debey, Pascale, Beaujean, Nathalie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364968/
https://ncbi.nlm.nih.gov/pubmed/22693592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038156
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