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Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling
The tumour suppressor gene product Mig-6 acts as an inhibitor of epidermal growth factor (EGF) signalling. However, its posttranslational modifications and regulatory mechanisms have not been elucidated. Here, we investigated the phosphorylation of human Mig-6 and found that Chk1 phosphorylated Mig-...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3364749/ https://ncbi.nlm.nih.gov/pubmed/22505024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.88 |
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