Phosphoproteomic analysis reveals that PP4 dephosphorylates KAP-1 impacting the DNA damage response

Protein phosphatase PP4C has been implicated in the DNA damage response (DDR), but its substrates in DDR remain largely unknown. We devised a novel proteomic strategy for systematic identification of proteins dephosphorylated by PP4C and identified KRAB-domain-associated protein 1 (KAP-1) as a subst...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Lee, Dong-Hyun, Goodarzi, Aaron A, Adelmant, Guillaume O, Pan, Yunfeng, Jeggo, Penelope A, Marto, Jarrod A, Chowdhury, Dipanjan
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group 2012
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364739/
https://ncbi.nlm.nih.gov/pubmed/22491012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.86
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים