Loading...

Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness

Hereditary myosin myopathies are characterized by variable clinical features. Inclusion body myopathy 3 (IBM-3) is an autosomal dominant disease associated with a missense mutation (E706K) in the myosin heavy chain IIa gene. Adult patients experience progressive muscle weakness. Biopsies reveal dyst...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Wang, Yang, Melkani, Girish C., Suggs, Jennifer A., Melkani, Anju, Kronert, William A., Cammarato, Anthony, Bernstein, Sanford I.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364171/
https://ncbi.nlm.nih.gov/pubmed/22496423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-02-0120
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!