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Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase

UNC-45 belongs to the UCS (UNC-45, CRO1, She4p) domain protein family, whose members interact with various classes of myosin. Here we provide structural and biochemical evidence that E. coli-expressed Drosophila UNC-45 (DUNC-45) maintains the integrity of several substrates during heat-induced stres...

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Detalhes bibliográficos
Main Authors: Melkani, Girish C., Lee, Chi F., Cammarato, Anthony, Bernstein, Sanford I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888609/
https://ncbi.nlm.nih.gov/pubmed/20403336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.04.090
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