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The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells

Isocitrate dehydrogenase 2 (IDH2) is located in the mitochondrial matrix. IDH2 acts in the forward Krebs cycle as an NADP(+)-consuming enzyme, providing NADPH for maintenance of the reduced glutathione and peroxiredoxin systems and for self-maintenance by reactivation of cystine-inactivated IDH2 by...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Smolková, Katarína, Ježek, Petr
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3363418/
https://ncbi.nlm.nih.gov/pubmed/22675360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/273947
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