Accurate in vitro cleavage by RNase III of phosphorothioate-substituted RNA processing signals in bacteriophage T7 early mRNA.

To test the ability of an RNA processing enzyme to cleave chemically-modified RNA substrates, RNA transcripts containing RNase III cleavage sites were enzymatically synthesized in vitro to contain specific phosphorothioate diester internucleotide linkages. One transcript (R1.1 RNA) was generated usi...

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Nicholson, A W, Niebling, K R, McOsker, P L, Robertson, H D
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 1988
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3279395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.4.1577
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