Accurate in vitro cleavage by RNase III of phosphorothioate-substituted RNA processing signals in bacteriophage T7 early mRNA.

To test the ability of an RNA processing enzyme to cleave chemically-modified RNA substrates, RNA transcripts containing RNase III cleavage sites were enzymatically synthesized in vitro to contain specific phosphorothioate diester internucleotide linkages. One transcript (R1.1 RNA) was generated usi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nicholson, A W, Niebling, K R, McOsker, P L, Robertson, H D
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1988
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC336336/
https://ncbi.nlm.nih.gov/pubmed/3279395
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