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Thermodynamics and Docking of Agonists to the β(2)-Adrenoceptor Determined Using [(3)H](R,R′)-4-Methoxyfenoterol as the Marker Ligand
G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components. The detailed interaction of a molecule with a G protein-coupled receptor is a com...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362895/ https://ncbi.nlm.nih.gov/pubmed/22434858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.077347 |
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