Quantitative genome re-sequencing defines multiple mutations conferring chloroquine resistance in rodent malaria

BACKGROUND: Drug resistance in the malaria parasite Plasmodium falciparum severely compromises the treatment and control of malaria. A knowledge of the critical mutations conferring resistance to particular drugs is important in understanding modes of drug action and mechanisms of resistances. They...

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Detalhes bibliográficos
Main Authors: Kinga Modrzynska, Katarzyna, Creasey, Alison, Loewe, Laurence, Cezard, Timothee, Trindade Borges, Sofia, Martinelli, Axel, Rodrigues, Louise, Cravo, Pedro, Blaxter, Mark, Carter, Richard, Hunt, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362770/
https://ncbi.nlm.nih.gov/pubmed/22435897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-106
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