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Novel Mechanism of Action on Hedgehog Signaling by a Suppressor of Fused Carboxy Terminal Variant

The Suppressor of Fused (SUFU) protein plays an essential role in the Hedgehog (HH) signaling pathway, by regulation of the GLI transcription factors. Two major isoforms of human SUFU are known, a full-length (SUFU-FL) and a carboxy-terminal truncated (SUFU- ΔC) variant. Even though SUFU- ΔC is expr...

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Bibliografski detalji
Glavni autori: Tostar, Ulrica, Finta, Csaba, Rahman, Mohammed Ferdous-Ur, Shimokawa, Takashi, Zaphiropoulos, Peter G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362617/
https://ncbi.nlm.nih.gov/pubmed/22666390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037761
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