PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis

We investigated the signaling basis for tubule pathology during fibrosis after renal injury. Numerous signaling pathways are activated physiologically to direct tubule regeneration after acute kidney injury (AKI) but several persist pathologically after repair. Among these, transforming growth facto...

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Detaylı Bibliyografya
Asıl Yazarlar: Lan, Rongpei, Geng, Hui, Polichnowski, Aaron J., Singha, Prajjal K., Saikumar, Pothana, McEwen, Donald G., Griffin, Karen A., Koesters, Robert, Weinberg, Joel M., Bidani, Anil K., Kriz, Wilhelm, Venkatachalam, Manjeri A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2012
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362177/
https://ncbi.nlm.nih.gov/pubmed/22301622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00660.2011
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