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Stimulation of Rho signaling by pathologic mechanical stretch is a “second hit” to Rho-independent lung injury induced by IL-6

Most patients with acute lung injury (ALI) and acute respiratory distress syndrome of septic and nonseptic nature require assisted ventilation with positive pressure, which at suboptimal range may further exacerbate lung dysfunction. Previous studies described enhancement of agonist-induced Rho GTPa...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Birukova, Anna A., Tian, Yufeng, Meliton, Angelo, Leff, Alan, Wu, Tinghuai, Birukov, Konstantin G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362159/
https://ncbi.nlm.nih.gov/pubmed/22345573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00292.2011
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