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Lung endothelial barrier protection by iloprost in the two-hit models of VILI involves inhibition of Rho signaling
Mechanical ventilation at high tidal volume may cause pulmonary capillary leakage and acute lung inflammation culminating in ventilator-induced lung injury. Iloprost is a stable synthetic analogue of prostaglandin I(2) used for treatment of pulmonary hypertension, which also showed endothelium-depen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2814140/ https://ncbi.nlm.nih.gov/pubmed/20004361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2009.09.002 |
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