Oxidative Stress Contributes to Lung Injury and Barrier Dysfunction via Microtubule Destabilization

Oxidative stress is an important part of host innate immune response to foreign pathogens, such as bacterial LPS, but excessive activation of redox signaling may lead to pathologic endothelial cell (EC) activation and barrier dysfunction. Microtubules (MTs) play an important role in agonist-induced...

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Autors principals: Kratzer, Eric, Tian, Yufeng, Sarich, Nicolene, Wu, Tinghuai, Meliton, Angelo, Leff, Alan, Birukova, Anna A.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547103/
https://ncbi.nlm.nih.gov/pubmed/22842495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0161OC
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